脉搏指数连续心排血量监测改善急性心肌梗死合并心原性休克患者临床预后研究Pulse index continuous cardiac output monitoring improved clinical outcomes of acute myocardial infarction patients complicated by cardiogenic shock
游洁芸,耿立,沈运丽,黄晶,王兴旭,王亮,张奇,郭蔚
摘要(Abstract):
目的 评估脉搏指数连续心排血量监测(PiCCO)在急性心肌梗死合并心原性休克(AMICS)患者接受急诊经皮冠状动脉介入治疗(PCI)后管理及改善临床预后中的作用。方法 纳入2016年6月至2021年6月上海市东方医院AMICS患者,经入排标准筛选,并进行1∶1倾向性评分匹配,最终Pi CCO组和对照组各50例患者纳入分析,比较两组临床特征、院内及30 d临床预后。结果 与对照组相比,PiCCO组住院期间应用强心药物和血管收缩药物比例较高,差异均有统计学意义(均P<0.05)。PiCCO组30 d内全因死亡率(16%比34%,P=0.024)、心原性死亡率(14%比30%,P=0.042)、再入院率(2%比14%,P=0.027)均显著低于对照组,首次住院时间明显短于对照组[(17.60±1.06)d比(24.32±2.19)d,P<0.001]。结论 AMICS患者接受急诊PCI后进行PiCCO监测有助于优化治疗方案,改善临床预后。
关键词(KeyWords): 血流动力学监测;脉搏指数连续心排血量监测;急性心肌梗死;心原性休克
基金项目(Foundation): 江西省卫生健康委科技计划项目(SKJP220210327);; 浦东新区卫生健康委员会卫生科研项目(PW2019A-13);; 浦东新区临床高峰学科项目(PWYgf2021-01);; 上海市东方医院“旭日”优秀青年医学人才培养计划项目(2019xrrcjh03)
作者(Author): 游洁芸,耿立,沈运丽,黄晶,王兴旭,王亮,张奇,郭蔚
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