经心尖入径二尖瓣置换术的临床应用及展望
秦悦,徐臣年,杨剑
摘要(Abstract):
<正>二尖瓣反流是最常见的心脏瓣膜疾病之一,是指由于二尖瓣瓣叶、瓣环、乳头肌、腱索等器质性或功能性改变导致二尖瓣前后叶吻合不良,使收缩期血流从左心室逆流至左心房~([1])。在75岁以上老人中约有10%患有此病~([2-3])。据估测,我国重度二尖瓣反流的患者数量在1000万以上,但得到外科手术治疗的比率低于2%~([4])。体外循环下进行二尖瓣修复或置换是二尖瓣反流的标准治疗方法,然而一些研究结果显示50%以上严重症状性二尖瓣反流患者由于肺功能不全、肝功能不全、肾功能不全等各种原因并不适于外科手术治疗~([5-6])。因而,二尖瓣反流的治疗应综合考虑病因、病理生理学、自然病史和预期治疗效果等多方面因素。2017年美国心脏协会(AHA)/美国心脏病学会
关键词(KeyWords): 二尖瓣反流;二尖瓣置换术;介入治疗
基金项目(Foundation):
作者(Author): 秦悦,徐臣年,杨剑
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