北京市延庆医院急性ST段抬高型心肌梗死患者5年生存率调查Investigation of 5-year survival after acute myocardial infarction in Beijing Yanqing hospital
王建斌,陈少敏,王立新,李富军,刘东庭,杨丽
摘要(Abstract)：
目的调查北京大学第三医院延庆医院急性ST段抬高型心肌梗死(ST-segment elevation myocardial inf arction,STEMI)患者5年生存率。方法对2002年8月至2010年12月于北京大学第三医院延庆医院就诊的691例STEMI患者进行5年随访,终点事件是全因死亡。采用Kaplan-Meier法绘制5年生存曲线,多因素Cox回归分析5年内死亡的预测因素。结果691例患者中442例(64.0%)未接受直接经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI),249例(36.0%)接受直接PCI。未接受直接PCI和接受直接PCI的患者5年生存率分别为73.8%和93.6%。未接受直接PCI患者死亡的预测因素为女性、年龄、慢性阻塞性肺疾病、住院期间心功能Killip分级≥Ⅱ级、前壁心肌梗死和未接受择期PCI,而接受直接PCI患者死亡的预测因素是年龄和住院期间消化道出血。结论接受直接PCI患者5年生存率显著高于未接受直接PCI的患者。两组患者死亡的预测因素有所不同。
关键词(KeyWords)： 急性ST段抬高型心肌梗死;预后;经皮冠状动脉介入治疗
基金项目(Foundation):
作者(Author): 王建斌,陈少敏,王立新,李富军,刘东庭,杨丽
参考文献(References)：
- [1]张秀英,赵东,王薇,等.2007年至2009年北京市居民急性心肌梗死住院病死率及其分布特征.心肺血管病杂志,2012,31(1):1-4.
- [2]李静,李希,余苑,等.2001年-2011年中国东部农村ST段抬高型心肌梗死诊疗变化趋势——china PEACE回顾性急性心肌梗死研究.中国循环杂志,2016,31(1):4-9.
- [3]Rapaport E.Nomenclature and criteria for diagnosis of ischemic heart disease.Report of the Joint International Society and Federation of Cardiology/World Health Organization Task Force on standardization of clinical nomenclature.Circulation,1979,59(3):607–609
- [4]张啸飞,胡大一,丁荣晶,等.中国心脑血管疾病死亡现状及流行趋势.中华心血管病杂志,2012,40(3):179-187.
- [5]杨玉科.影响农村急性心肌梗死患者治疗依从性因素调查.中国误诊学杂志,2008,8(29):7305-7305
- [6]方晓聪,王向东.慢性阻塞性肺疾病在中国的诊治现状.国际呼吸杂志,2011,31(7):493-497.
- [7]King PT.Inflammation in chronic obstructive pulmonary disease and its role in cardiovascular disease and lung cancer.Clin Transl Med,2015,4(1):68.
- [8]Ghoorah K,De Soyza A,Kunadian V.Increased cardiovascular risk in patients with chronic obstructive pulmonary disease and the potential mechanisms linking the two conditions:a review.Cardiol Rev,2013,21(4):196-202.
- [9]Chen W,Thomas J,Sadatsafavi M,et al.Risk of cardiovascular comorbidity in patients with chronic obstructive pulmonary disease:a systematic review and meta-analysis.Lancet Respir Med,2015,3(8):631-639.
- [10]Campo G,Guastaroba P,Marzocchi A,Santarelli A,et al.Impact of COPD on long-term outcome after ST-segment elevation myocardial infarction receiving primary percutaneous coronary intervention.Chest,2013,144(3):750–757.
- [11]Jatene T,Biering-Sφrensen T,Nochioka K,et al.Frequency of Cardiac Death and Stent Thrombosis in Patients With Chronic Obstructive Pulmonary Disease Undergoing Percutaneous Coronary Intervention(from the BASKET-PROVE I and II Trials).Am J Cardiol,2017,119(1):14-19.
- [12]Ergelen M,Uyarel H,Soylu O,et al.Gastrointestinal bleeding in patients undergoing primary angioplasty for acute myocardial infarction:incidence,risk factors and prognosis.Turk Kardiyol Dern Ars,2010,38(2):101-106.
- [13]Wu CJ,Lin HJ,Weng SF,et al.Acute Myocardial Infarction Risk in Patients with Coronary Artery Disease Doubled after Upper Gastrointestinal Tract Bleeding:A Nationwide Nested Case-Control Study.PLo S One,2015,10(11):e0142000.