王昆,徐标,宋杰,王涟,黄为,高玲,张静梅

• 1:南京大学医学院附属鼓楼医院心内科

摘要(Abstract)：

目的评估血管内超声(IVUS)指导下冠状动脉旋磨术联合药物洗脱支架(DES)治疗严重钙化病变的疗效。方法 13例冠状动脉严重钙化患者在IVUS指导下行冠状动脉旋磨及支架置入术,评估手术即刻成功率、术后管腔最小直径、最小直径狭窄率、管腔有效面积变化及随访结果。结果 13例中,单支病变1例(7.7%),双支病变3例(23.1%),三支病变6例(46.2%),左主干+三支病变1例(7.7%),左主干病变2例(15.4%)。术前、术后肌钙蛋白T、肌酸激酶同工酶与肌酸酐比较,差异无统计学意义。靶血管管腔最小直径由术前(2.0±0.3)mm增大至术后的(3.6±0.8)mm,直径狭窄率由术前的(74.5±6.8)%减少至术后的(20.3±12.5)%,管腔有效面积由术前的(4.0±1.4)mm2增大至术后的(10.7±5.5)mm2,差异均有统计学意义。即刻手术成功率100%,术后随访期间无心绞痛再发、心肌梗死及靶血管再次血运重建。结论 IVUS指导下冠状动脉旋磨术联合DES可安全用于冠状动脉严重钙化病变患者,提高了介入手术的成功率。

关键词(KeyWords)： 冠状动脉;严重钙化;血管内超声;旋磨术;药物洗脱支架

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 王昆,徐标,宋杰,王涟,黄为,高玲,张静梅

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