彭欣,刘健

• 1:北京大学人民医院心血管内科急性心肌梗死早期预警和干预北京市重点实验室

摘要(Abstract)：

冠状动脉腔内影像学是经皮冠状动脉介入治疗的重要辅助方式，因其较高的分辨率、穿透力而被用以精准协助判断斑块性质、管腔特征、病变程度等，近年来在冠状动脉粥样硬化性心脏病治疗策略的优化、疗效评价等方面承担着重要角色。2022年，对IVUS-XPL、ULTIMATE试验数据的再次分析、LightLabInitiative研究等进一步证明了腔内影像技术在冠心病诊疗中的作用。随着相关领域研究的不断进展，腔内影像技术会更广泛、高效地应用于指导各类冠状动脉病变的介入治疗中。

关键词(KeyWords)： 腔内影像学;经皮冠状动脉介入治疗;冠心病

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金重点项目（11832003）;国家自然科学基金面上项目（81970294）

作者(Author): 彭欣,刘健

参考文献(References)：

• [1]Lawton JS,Tamis-Holland JE,Bangalore S,et al.2021 ACC/AHA/SCAI guideline for coronary artery revascularization:a report of the American College of Cardiology/American Heart Association joint committee on clinical practice guidelines[J].J Am Coll Cardiol,2022,79(2):e21-e129.DOI:10.1016/j.jacc.2021.09.006.
• [2]Machanahalli BA,Ismayl M,Walters RW,et al.Comparing optical coherence tomography and intravascular ultrasound guidance for percutaneous coronary intervention:trends and outcomes2010-2019[J].Curr Probl Cardiol,2022,47(9):101270.DOI:10.1016/j.cpcardiol.2022.101270.
• [3] Neumann FJ,Sousa-Uva M,Ahlsson A,et al.2018 ESC/EACTS guidelines on myocardial revascularization[J].Eur Heart J,2019,40(2):87-165.DOI:10.1093/eurheartj/ehy394.
• [4]Romagnoli E,Ramazzotti V,Burzotta F,et al.Definition of optimal optical coherence tomography-based stent expansion criteria:in-stent minimum lumen area versus residual stent underexpansion[J].Circ Cardiovasc Interv,2022,15(9):e011496.DOI:10.1161/CIRCINTERVENTIONS.121.011496.
• [5]Bergmark B,Dallan LAP,Pereira GTR,et al.Decisionmaking during percutaneous coronary intervention guided by optical coherence tomography:insights from the LightLab Initiative[J].Circ Cardiovasc Interv,2022,15(11):872-881.DOI:10.1161/CIRCINTERVENTIONS.122.011851.
• [6] Lee SY,Zhang JJ,Mintz GS,et al.Procedural characteristics of intravascular ultrasound-guided percutaneous coronary intervention and their clinical implications[J].J Am Heart Assoc,2022,11(14):e025258.DOI:10.1161/JAHA.122.025258.
• [7]Abouelnour A,Gori T.Intravascular imaging in coronary stent restenosis:prevention,characterization,and management[J].Front Cardiovasc Med,2022,9:843734.DOI:10.3389/fcvm.2022.843734.
• [8]Mintz GS,Popma JJ,Pichard AD,et al.Patterns of calcifification in coronary artery disease.A statistical analysis of intravascular ultrasound and coronary angiography in 1155lesions[J].Circulation,1995,91(7):1959-1965.DOI:10.1161/01.cir.91.7.1959.
• [9]Kyodo A,Okura H,Okamura A,et al.Incidence and characteristics of incomplete stent apposition in calcifified lesions:an optical coherence tomography study[J].Cardiovasc Revasc Med,2022,41:55-60.DOI:10.1016/j.carrev.2021.12.032.
• [10]Greenland P,Blaha MJ,Budoff MJ,et al.Coronary calcium score and cardiovascular risk[J].J Am Coll Cardiol,2018,72(4):434-447.DOI:10.1016/j.jacc.2018.05.027.
• [11]Mehta A,Vasquez N,Ayers CR,et al.Independent association of lipoprotein(a)and coronary artery calcifification with atherosclerotic cardiovascular risk[J].J Am Coll Cardiol,2022,79(8):757-768.DOI:10.1016/j.jacc.2021.11.058.
• [12] Ma W,Wang Q,Wang B,et al.Novel predictors of stent under-expansion regarding calcified coronary lesions assessed by optical coherence tomography[J].Catheter Cardiovasc Interv,2022,99:1473-1481.DOI:10.1002/ccd.30118.
• [13]Kumar P,Jino B,Roy S,et al.Absolute zero-contrast percutaneous coronary intervention under intravascular ultrasound guidance in chronic kidney disease patients-From despair to hope?[J].Int J Cardiol Heart Vase,2022,40:101052.DOI:10.1016/j.ijcha.2022.101052.
• [14]Mariani J Jr,Guedes C,Soares P,et al.Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention The MOZART(Minimizing cOntrastutiliZation With IVUS Guidance in coRonaryangioplasTy)randomized controlled trial[J].JACC Cardiovasc Interv,2014,7(11):1287-1293.DOI:10.1016/j.jcin.2014.05.024.
• [15] Yoon JY,Lee JH,Choi H,et al.Impact of intravascular ultrasound and final kissing balloon dilatation on long-term clinical outcome in percutaneous revascularization with 1-stent strategy for left main coronary artery stenosis in drug-eluting stent era[J].Coron Artery Dis,2022,31(1):9-17.DOI:10.1097/MCA.0000000000001101.
• [16] Takagi K,Nagoshi R,Kim BK,et al.Efficacy of coronary imaging on bifurcation intervention[J].Cardiovasc Interv Ther,2021,36(1):54-66.DOI:10.1007/s12928-020-00701-2.
• [17]Nishimura T,Okamura T,Fujimura T,et al.Feasibility,reproducibility and characteristics of coronary bifurcation type assessment by three-dimensional optical coherence tomography[J].PLoS One,2022,17(2):e0263246.DOI:10.1371/joumal.pone.0263246.
• [18]Virmani R,Burke AP,Farb A,et al.Pathology of the vulnerable plaque[J].J Am Coll Cardiol,2006,47(8Suppl):C13-C18.DOI:10.1016/j.jacc.2005.10.065.
• [19]卢亚辉,侯昌,刘健.2020年冠状动脉腔内影像学研究进展[J].中国介入心脏病学杂志,2021,29(11):637-641.DOI:10.3969/j.issn.1004-8812.2021.11.007.
• [20]Kubo T,Terada K,Ino Y,et al.Combined use of multiple intravascular imaging techniques in acute coronary syndrome[J].Front Cardiovasc Med,2022,8:824128.DOI:10.3 389/fcvm.2021.824128.
• [21] Zhang YB,Liu HD,Xing JH,et al.Safety and effificacy of drug-coated balloons in patients with acute coronary syndromes and vulnerable plaque[J].Clin Appl Thromb Hemost,2022,28:10760296221130063.DOI:10.1177/10760296221130063.
• [22]Usui E,Yonetsu T,Ohmori M,et al.Predictors of nearinfrared spectroscopy-detected lipid-rich plaques by optical coherence to mography-defifined morphological features in patients with acute coronary syndrome[J].Front Cardiovasc Med,2022,9:842914.DOI:10.3389/fcvm.2022.842914.
• [23]Tateishi K,Saito Y,Kitahara H,et al.Relation of glucose variability to vulnerable plaque formation in patients with coronary artery disease[J].Heart Vessels,2022,37(9):1516-1525.DOI:10.1007/s00380-022-02063-6.
• [24] Pu Z,Lai L,Yang X,et al.(2020)Acute glycemic variability on admission predicts the prognosis in hospitalized patients with coronary artery disease:a meta-analysis[J].Endocrine,2020,67(3):526-534.DOI:10.1007/s12020-019-02150-1.
• [25]聂文畅,刘健.2021年冠状动脉腔内影像学进展[J].中国介入心脏病学杂志,2022,30(7):622-625.DOI:10.3969/j.issn.1004-8812.2022.08.010.
• [26]Collet JP,Thiele H,Barbato E,et al.2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation:the task force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology(ESC)[J].Eur Heart J,2020,42(14):1289-1367.DOI:10.1093/eurheartj/ehaa575.
• [27]Song XW,Zhou X,Li ZP,et al.Early statin therapy and inhospital outcomes in acute coronary syndrome patients presenting with advanced killip class at admission:findings from the CCCACS project[J].Am J Cardiovasc Drugs,2022,22(6):685-694.DOI:10.1007/s40256-022-00546-5.
• [28] Toso A,Morici N,Leoncini M,et al.Association of statin pretreatment with presentation characteristics,infarct size and outcome in older patients with acute coronary syndrome:the elderly ACS-2 trial[J].Age Ageing,2022,51(6):afac121.DOI:10.1093/ageing/afac121.
• [29]Ota H,Omori H,Kawasaki M,et al.Clinical impact of PCSK9inhibitor on stabilization and regression of lipid-rich coronary plaques:a near-infrared spectroscopy study[J].Eur Heart J Cardiovasc Imaging,2022,23(2):217-228.DOI:10.1093/ehjci/jeab034.
• [30]Kaziród-Wolski K,Sielski J,Gasior M,et al.Factors affecting short-and long-term survival of patients with acute coronary syndrome treated invasively using intravascular ultrasound and fractional flow reserve:Analysis of data from the Polish Registry of Acute Coronary Syndromes 2017-2020[J].Kardiol Pol,2022.Online ahead of print.DOI:10.33963/KP.a2022.0261.