尚小珂,Zhong Liang,张刚成,彭婷,李丁扬,卢蓉,邓晓娴,周红梅

• 1:武汉市亚洲心脏病医院心外科导管室 国家肺动脉高压诊疗基地 国家结构心脏病介入培训基地
• 2:新加坡国立心脏中心
• 3:新加坡国立心脏研究所国立大学医学研究院

摘要(Abstract)：

目的探讨在艾森曼格综合征早期能否行动脉导管未闭(PDA)介入手术治疗。方法 3例患者术前1周内按照注册研究规定行临床评估和肺动脉高压相关检查及登记。行右心导管检查以及肺血管扩张试验(面罩吸入万他维1支),测量试验前后肺动脉压力、降主动脉压力、肺体循环血流量比、肺体压力比、肺毛细血管嵌压[均≤15 mmHg(1 mmHg=0.133 kPa)]等,明确肺血管扩张试验结果后行试封堵试验,如为阳性,与家属沟通同意后释放封堵器;如为阴性,快速撤出封堵器并根据患者临床症状对症处理。结果病例1肺血管扩张试验阴性,试封堵试验阳性,即刻手术效果理想,经家属同意释放封堵器。病例2、病例3肺血管扩张试验阴性,试封堵试验阴性,未释放封堵器。结论部分早期艾森曼格综合征动脉导管未闭患者可行介入封堵,试封堵试验可能是一个预测预后的重要指标。

关键词(KeyWords)： 肺动脉高压;艾森曼格综合征;先天性心脏病

Abstract:

Keywords:

基金项目(Foundation): 国家“十二·五”课题《肺循环疾病及心功能的研究》(2011BAI11B15)

作者(Author): 尚小珂,Zhong Liang,张刚成,彭婷,李丁扬,卢蓉,邓晓娴,周红梅

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