PRAMI研究结果能够改变将来的临床实践吗
颜红兵
摘要(Abstract):
<正>新近发表的PRAMI(Preventive Angioplasty in Acute Myocardial Infarction)研究[1]是一项计划入选600例ST段抬高急性心肌梗死(STEMI)合并多支血管病变的患者,对其进行随机比较一次性经皮冠状动脉介入治疗(PCI)策略与分次PCI策略的研究,由于在前465例患者的中期结果显示一次性策略明显获益而中止研究。这项研究结果的发表给我
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基金项目(Foundation):
作者(Author): 颜红兵
参考文献(References):
- [1]Wald DS,Morris JK,Wald NJ,et al.Randomized trial of preventive angioplasty in myocardial infarction.N Engl J Med,2013,369:1115-1123.
- [2]Mylotte D,Morice MC,Eltchaninoff H,et al.Primary percutaneous coronary intervention in patients with acute myocardial infarction,resuscitated cardiac arrest,and cardiogenic shock:the role of primary multivessel revascularization.JACC Cardiovasc Interv,2013,6:115-125.
- [3]Toma M,Buller CE,Westerhout CM,et al.Non-culprit coronary artery percutaneous coronary intervention during acute STsegment elevation myocardial infarction:insights from the APEXAMI trial.Eur Heart J,2010,31:1701-1707.
- [4]Vlaar PJ,Mahmoud KD,Holmes DR,et al.Culprit vessel only versus multivessel and staged percutaneous coronary intervention for multivessel disease in patients presenting with ST-segment elevation myocardial infarction:A pairwise and network metaanalysis.J Am Coll Cardiol,2011,58:692-703.
- [5]Kornowski R,Mehran R,Dangas G,et al.Prognostic impact of staged versus"one-time"multivessel percutaneous intervention in acute myocardial infarction:analysis from the HORIZONS-AMI(harmonizing outcomes with revascularization and stents in acute myocardial infarction)trial.J Am Coll Cardiol,2011,58:704-711.