张波,周旭晨

• 1:大连医科大学附属第一医院心内科

摘要(Abstract)：

<正>心血管疾病与肿瘤是全球负担最大的两个慢性疾病。近年研究表明,心血管疾病-肿瘤的研究焦点已从对单一疾病的预防和治疗转为对两者之间潜在关系的探讨[1]。肿瘤和心血管疾病常伴有共同的危险因素,肿瘤患者生存时限的延长造成了心血管疾病发病率和死亡率的升高;同时肿瘤的化学和放射治疗相关的心血管毒性也是关注的重点。鉴于肿瘤患者的特殊性,产生了新兴的交叉学科——肿瘤心脏病学。2016年8月28日欧洲心脏病学会

关键词(KeyWords)： 肿瘤;心血管疾病;化学药物治疗;放射治疗

Abstract:

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基金项目(Foundation):

作者(Author): 张波,周旭晨

参考文献(References)：

• [1]Koene RJ,Prizment AE,Blaes A,et al.Shared risk factors in cardiovascular disease and cancer.Circulation,2016,133(11):1104-1114.
• [2]Zamorano JL,Lancellotti P,Rodriguez Mu1oz D,et al.2016ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC committee for practice guidelines:The task force for cancer treatmentsand cardiovascular toxicity of the European Society of Cardiology(ESC).Eur Heart J,2016,37(36):2768-2801.
• [3]Oeffinger KC,Mertens AC,Sklar CA,et al.Chronic health conditions in adult survivors of childhood cancer.N Engl J Med,2006,355(15):1572-1582.
• [4]Hall PS,Harshman LC,Srinivas S,et al.The frequency and severity of cardiovascular toxicity from targeted therapy in advanced renal cell carcinoma patients.JACC Heart Fail,2013,1(1):72-78.
• [5]Moore RA,Adel N,Riedel E,et al.High incidence of thromboembolic events in patients treated with cisplatin-based chemotherapy:a large retrospective analysis.J Clin Oncol,2011,29(25):3466-3473.
• [6]Herrmann J,Yang EH,Iliescu CA,et al.Vascular toxicities of cancer therapies:the old and the New--an evolving avenue.Circulation,2016,133(13):1272-1289.
• [7]Iliescu CA,Grines CL,Herrmann J,et al.SCAI Expert consensus statement:Evaluation,management,and special considerations of cardio-oncology patients in the cardiac catheterization laboratory(endorsed by the cardiological society of india,and sociedad latino Americana de Cardiologia intervencionista).Catheter Cardiovasc Interv,2016,87(5):E202-E223.
• [8]Malanca M,Cimadevilla C,Brochet E,et al.Radiotherapyinduced mitral stenosis:a three-dimensional perspective.J Am Soc Echocardiogr,2010,23(1):108.e1-e2.
• [9]Tamargo J,CaballeroR,Delpón E.Cancer chemotherapy and cardiac arrhythmias:a review.Drug Saf,2015,38(2):129-152.
• [10]Milan A,Puglisi E,Ferrari L,et al.Arterial hypertension and cancer.Int J Cancer,2014,134(10):2269-2277.
• [11]Di Nisio M,Ferrante N,Feragalli B,et al.Arterial thrombosis in ambulatory cancer patients treated with chemotherapy.Thromb Res,2011,127(4):382-383.
• [12]Lecumberri R,Marqués M,Panizo E,et al.High incidence of venous thromboembolism despite electronic alerts for thromboprophylaxis in hospitalised cancer patients.Thromb Haemost,2013,110(1):184-190.
• [13]Valent P,Hadzijusufovic E,Schernthaner GH,et al.Vascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitors.Blood,2015,125(6):901-906.
• [14]De Bruin ML,Dorresteijn LD,van't Veer MB,et al.Increased risk of stroke and transient ischemic attack in 5-year survivors of Hodgkin lymphoma.J Natl Cancer Inst,2009,101(13):928-937.
• [15]Adler Y,Charron P,Imazio M,et al.2015 ESC Guidelines for the diagnosis and management of pericardial diseases:The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology(ESC)Endorsed by:The European Association for Cardio-Thoracic Surgery(EACTS).Eur Heart J,2015,36(42):2921-2964.