周广为,何奔

• 1:上海市东方医院心脏内科

摘要(Abstract)：

三尖瓣反流（TR）是一种常见的瓣膜性心脏病，其患病率随年龄增长而增加，严重影响患者预后。然而，三尖瓣病变的治疗决策面临诸多挑战，包括手术风险评估、治疗时机选择以及不同治疗方式的比较。传统的风险评分系统在三尖瓣疾病中的预测效能有限，亟需开发专门的风险评估工具。本文旨在系统评价TRI-SCORE风险评分系统的构建、验证及其在外科手术与经导管介入治疗中的预测效能与临床应用价值，为三尖瓣疾病的精准管理提供循证依据。

关键词(KeyWords)： TRI-SCORE;三尖瓣反流;临床预测模型;风险评分;预后评估;外科手术;经导管三尖瓣介入治疗

Abstract:

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基金项目(Foundation):

作者(Author): 周广为,何奔

参考文献(References)：

• [1]Topilsky Y,Maltais S,Medina Inojosa J,et al.Burden of tricuspid regurgitation in patients diagnosed in the community setting[J].JACC Cardiovasc Imaging,2019,12(3):433-442.DOI:10.1016/j.jcmg.2018.06.014.
• [2]Messika-Zeitoun D,Verta P,Gregson J,et al.Impact of tricuspid regurgitation on survival in patients with heart failure:a large electronic health record patient-level database analysis[J].Eur J Heart Fail,2020,22(10):1803-1813.DOI:10.1002/ejhf.1830.
• [3]LaPar DJ,Likosky DS,Zhang M,et al.Development of a risk prediction model and clinical risk score for isolated tricuspid valve surgery[J].Ann Thorac Surg,2018,106(1):129-136.DOI:10.1016/j.athoracsur.2017.11.077.
• [4]Dreyfus J,Audureau E,Bohbot Y,et al.TRI-SCORE:a new risk score for in-hospital mortality prediction after isolated tricuspid valve surgery[J].Eur Heart J,2022,43(7):654-662.DOI:10.1093/eurheartj/ehab679.
• [5]Ailawadi G,Lapar DJ,Swenson BR,et al.Model for end-stage liver disease predicts mortality for tricuspid valve surgery[J].Ann Thorac Surg,2009,87(5):1460-1468.DOI:10.1016/j.athoracsur.2009.01.043.
• [6]Sala A,Carino D,Lorusso R,et al.TRI-SCORE:a single-centre validation study[J].Interdiscip Cardiovasc Thorac Surg,2023,36(6):ivad085.DOI:10.1093/icvts/ivad085.
• [7]Kim DY,Kim J,Cho I,et al.Validation of TRI-SCORE for outcome prediction after isolated tricuspid valve surgery in Asian patients[J].J Am Heart Assoc,2024,13(8):e032929.DOI:10.1161/JAHA.123.032929.
• [8]Dreyfus J,Bohbot Y,Coisne A,et al.Predictive value of the TRISCORE for in-hospital mortality after redo isolated tricuspid valve surgery[J].Heart,2023,109(12):951-958.DOI:10.1136/heartjnl-2022-322167.
• [9]Vahanian A,Beyersdorf F,Praz F,et al.2021 ESC/EACTSGuidelines for the management of valvular heart disease[J].EuroIntervention,2022,17 (14):e1126-e1196.DOI:10.4244/EIJ-E-21-00009.
• [10]中国医师协会心血管内科医师分会结构性心脏病学组,苏州工业园区东方华夏心血管健康研究院.三尖瓣反流经导管治疗的中国专家共识[J].中国介入心脏病学杂志,2024,32(10):551-561.DOI:10.3969/j.issn.1004-8812.2024.10.002.
• [11]刘先宝,任凯达,蒲朝霞,等.经导管三尖瓣缘对缘修复术操作流程[J].中国介入心脏病学杂志,2023,31(5):387-393.DOI:10.3969/j.issn.1004-8812.2023.05.011.
• [12]Vogelhuber J,Tanaka T,Sugiura A,et al.Association of TRI-SCOREwith clinical outcomes after transcatheter tricuspid valve repair[J].JACC Cardiovasc Interv,2023,16(13):1698-1700.DOI:10.1016/j.jcin.2023.04.005.
• [13]Potratz M,Narang A,Ger??ek M,et al.Performance of the TRI-SCORE in a multicenter cohort undergoing transcatheter tricuspid valve repair and Replacement[J].JACCCardiovasc Interv,2025,18(17):2192-2194.DOI:10.1016/j.jcin.2025.07.011.
• [14]Dreyfus J,Galloo X,Taramasso M,et al.TRI-SCORE and benefit of intervention in patients with severe tricuspid regurgitation[J].Eur Heart J,2024,45(8):586-597.DOI:10.1093/eurheartj/ehad585.