心先安对冠心病患者左室舒张功能的影响The effects of meglumine cyclic adenylate (MCA) on left ventricular diastolic function in coronary heart disease
张可方,丁明,窦发坦,吴瑞婷,高效斗
摘要(Abstract)：
为研究心先安对冠心病患者左室舒张功能的影响，选取38例心绞痛病人，静滴心先安90～120mg／d，10～14天为一疗程，应用超声多普勒测定左室舒缩末内径、舒张早期和晚期血流峰值速度（EV、AV）、舒张早期减速度（DC）及时间流速积分比R．等。结果，治疗前射血分数减低47±8．5％，EV降低68±9cm／s，AV增加88±16cm／s，R降低1．4±0．4，应用心先安后心电图缺血改善，上述指标明显好转（P＜0．05），而DC变化不大。表明冠心病患者存在左室舒张功能障碍，心选安可改善左室舒张功能及心肌供血，早期应用可防治心衰。
关键词(KeyWords)： 冠心病;心功能.左室;环腺苷酸
基金项目(Foundation):
作者(Author): 张可方,丁明,窦发坦,吴瑞婷,高效斗
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