鱼油制剂对球囊血管成形术局部动脉壁6-酮-前列腺素及血小板血栓素影响的实验研究
杨树森,黄永麟,孙宝贵,赵进军,周玉杰,王岚峰,林继红
摘要(Abstract):
本实验选用日本纯系雄性大耳白兔100只建立右髂动脉粥样硬化狭窄模型,动态观察鱼油制剂对球囊血管成形术局部动脉壁6-keto-PGF_(1α)及血小板 TXB_2的影响。结果表明,鱼油制剂对动脉壁6-keto-PGF_(1α)含量无影响,可使血小板 TXB_2生成明显减少,因此明显降低血管损伤局部 TXB_2与6-keto-PGF_(1α)比值,继而减少血小板粘附并脱颗粒释放生长因子,对预防再狭窄发生可能有一定意义。
关键词(KeyWords): 血管成形术;动脉;6-keto-PGF_(1α)血小板;TXB_2
基金项目(Foundation):
作者(Author): 杨树森,黄永麟,孙宝贵,赵进军,周玉杰,王岚峰,林继红
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