郑泽,柳景华,范谦,李世英,王健,赵东晖,彭红玉,吴铮,郑斌,王平,李文铮

• 1:首都医科大学附属北京安贞医院心内科北京市心肺血管疾病研究所

摘要(Abstract)：

目的比较冠状动脉旋磨术中使用低转速和高转速旋磨的安全性和有效性,探讨冠状动脉旋磨术应用不同旋磨速度的临床结果。方法采用单中心前瞻性随机对照研究方法,将2012年9月1日至2017年9月1日因严重冠状动脉钙化行冠状动脉旋磨术的患者随机分成低转速组(140 000 r/min)和高转速组(180 000 r/min),比较手术结果和围术期及30 d内的主要并发症。结果冠状动脉旋磨术86例中共入选患者50例,高转速组25例,低转速组25例。两组冠状动脉旋磨术手术成功率为100.0%比96.0%(P=1.000),其中低转速组1例患者旋磨后仍有球囊扩张不良,放弃置入支架。两组均未发生严重并发症,高转速组4例发生分支急性闭塞(16.0%比4.0%,P=0.346),其中3例有夹层(12.0%比4.0%,P=0.602);2例慢血流或无复流(8.0%比0.0,P=0.470),与低转速组比较差异均无统计学意义。低转速组中1例出现失速、磨头嵌顿。结论冠状动脉旋磨术中选择140 000 r/min和180 000 r/min的转速均可取得较高的手术成功率,高转速可能会增加慢血流或无复流和夹层尤其是分支急性闭塞的发生率,在严重迂曲钙化病变中选择低转速时要预防旋磨头卡住和旋磨效果不良的情况。

关键词(KeyWords)： 冠状动脉旋磨术;钙化病变;低频转速;高频转速

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(81570388)

作者(Author): 郑泽,柳景华,范谦,李世英,王健,赵东晖,彭红玉,吴铮,郑斌,王平,李文铮

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