阳泽文,于波

• 1:哈尔滨医科大学附属第二医院心血管内科

摘要(Abstract)：

<正>目前,缺血性心脏病仍是世界范围内发病率及死亡率最高的疾病。冠状动脉内血栓形成被认为是急性冠状动脉综合征(acute coronary syndrome,ACS)的最终通路。斑块破裂长期以来被认为引起了绝大多数冠状动脉内血栓形成。但目前的证据显示,这样的看法不仅片面,还掩盖了其他能引起冠状动脉内血栓形成的病因及对应的治疗策略[1]。无论是之前针对心脏性猝死的病理学研究,还是新兴的冠状动脉腔内影像学研究,斑块侵蚀作为引起冠状动脉内血栓形成的第二大原因,其独特的病理生理学机制及针对性的治疗措施都备受研究者的关注。本文针对基于斑块侵蚀的ACS治疗策略研究新进展作一综述,以为ACS的个体化和精准化治疗提供新的思路。

关键词(KeyWords)： 急性冠状动脉综合征;斑块侵蚀;光学相干断层成像

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(81330033);; 国家重点研发计划资助(2016YFC1301100);; 黑龙江省教育厅重点项目(11551z009)

作者(Author): 阳泽文,于波

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