血小板功能检测与个体化抗血小板治疗
陈伟翔,郭素峡,羊镇宇,吴雄波,曹华明
摘要(Abstract):
<正>动脉血栓形成是急性冠状动脉综合征(ACS)和经皮冠状动脉介入治疗(PCI)后发生不良心血管事件的基本原因[1]。内皮破损导致的血小板活化及聚集是引起ACS等血栓事件最重要的病理过程。多项临床试验已证实ACS和(或)PCI术后患者应用阿司匹林和二磷酸腺苷(ADP)P2Y12受体拮抗剂的双联抗血小板治疗获益显著。然而,PCI术后血栓事件仍有发生,可能与抗血小板作用的延迟、PCI初期不能提供充分的拮抗作用及个体最大平均有效剂
关键词(KeyWords): 急性冠状动脉综合征;血小板功能检测;抗血小板治疗
基金项目(Foundation):
作者(Author): 陈伟翔,郭素峡,羊镇宇,吴雄波,曹华明
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