卡托普利对动脉腔内成形术局部平滑肌细胞超微结构影响的实验研究
杨树森,黄永麟,孟繁超,孙宝贵,赵进军,林继红
摘要(Abstract):
本实验在建立兔右髂动脉粥样硬化狭窄模型的基础上,观察卡托普利对成形术局部血管内膜平滑肌细胞(SMCs)超微结构的影响.结果表明,扩张术后1~2周血管内膜SMCs.由收缩型转变为合成型;卡托普利可使SMCs胞浆中与合成及增生功能有关的细胞器(粗面内质网和线粒体)明显减少,单位体积SMCs胞浆内细胞器作密度显著降低.提示卡托普利可有效抑制SMCs增殖程度,对防止再狭窄发生有重要意义.
关键词(KeyWords): 卡托普利;血管成形术;平滑肌细胞;超微结构
基金项目(Foundation):
作者(Author): 杨树森,黄永麟,孟繁超,孙宝贵,赵进军,林继红
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