冠状动脉微循环阻力指数的应用与进展Application and progress of index of microcirculatory resistance
任凌彤,艾虎
摘要(Abstract):
随着对冠状动脉相关疾病研究的深入,人们逐渐认识到冠状动脉微循环障碍对于心血管疾病的发生、发展、疗效及预后等具有重要影响,冠状动脉微循环疾病在缺血性心脏病中受到越来越多的重视。由于无法直接通过影像学观察到冠状动脉微血管,目前临床上出现了一些评价冠状动脉微循环功能的指标,其中微循环阻力指数被广泛用于冠状动脉微循环功能评价。基于计算流体力学的微循环阻力指数测定技术准确、安全、简单易行,应用前景广泛。本文就微循环阻力指数的建立、发展、临床应用、进展进行综述。
关键词(KeyWords): 微循环阻力指数;冠状动脉微循环功能障碍;计算流体力学
基金项目(Foundation): 中国医学科学院医学与健康科技创新工程项目(2021-I2M-C&T-A-019);; 首都临床诊疗技术研究及转化应用项目(Z211100002921008);; 中央高水平医院临床科研业务费资助项目(BJ-2019-193)
作者(Author): 任凌彤,艾虎
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