急性ST段抬高型心肌梗死经皮冠状动脉介入治疗术中采用球囊缓慢撤压方法预防无复流和慢血流现象的作用研究Efficacy of slowly deflating balloon for prevention of no reflow and slow flow phenomenon during percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction
崔冬,黄亚华,刘智坚,刘俊君,贾玉琳,姜东炬
摘要(Abstract):
目的 评估急性ST段抬高型心肌梗死(STEMI)患者接受经皮冠状动脉介入治疗(PCI)术中采用球囊缓慢撤压方法对无复流(NR)和慢血流(SF)现象的预防作用。方法 选取2017年1月至2020年12月就诊于解放军联勤保障部队第九六七医院(原解放军第二一零医院)心内科,符合STEMI诊断标准并接受PCI的患者242例。根据PCI术中球囊撤压方法不同将患者分为球囊缓慢撤压组(试验组,115例)和常规方法撤压组(对照组,127例),收集两组患者的基本临床资料以及PCI的相关资料,比较两组患者PCI术中NR和SF的发生率及术后即刻抬高ST段回落≥50%的比例。结果 (1)两组患者基本临床资料比较,差异均无统计学意义(均P>0.05);(2)两组患者PCI相关资料比较,差异均无统计学意义(均P>0.05);(3)两组患者NR和SF发生率比较:球囊预扩张后,两组恢复心肌梗死溶栓治疗试验(TIMI)血流分级Ⅲ级且心肌呈色分级(MBG)≥Ⅱ级的发生率分别为90.4%和85.8%,差异无统计学意义(P=0.270);支架释放后,试验组NR和SF的发生率明显低于对照组(3.5%比11.0%,P=0.025),差异有统计学意义;支架内球囊后扩张后,试验组NR和SF的发生率明显低于对照组(1.7%比7.9%,P=0.028),差异有统计学意义;(4)两组术后即刻心电图比较:试验组术后即刻心电图抬高ST段回落≥50%的比例明显高于对照组(97.4%比89.8%,P=0.017),差异有统计学意义。结论 STEMI患者行PCI术中采用球囊缓慢撤压方法与常规方法撤压比较,能够明显降低NR和SF的发生率,缩短ST段回落时间。
关键词(KeyWords): 急性ST段抬高型心肌梗死;经皮冠状动脉介入治疗;球囊撤压;无复流;慢血流;预防
基金项目(Foundation):
作者(Author): 崔冬,黄亚华,刘智坚,刘俊君,贾玉琳,姜东炬
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