血脂及增龄对冠心病合并2型糖尿病患者冠状动脉造影特点的影响Influence of serum lipids and age on the angiographic characteristics in coronary heart disease patients with type 2 diabetes mellitus
宫建丽,李文华,孔香云,张秀洲,唐元升,高燕燕,朱兴雷
摘要(Abstract)：
目的探讨血脂及增龄对冠心病合并2型糖尿病患者冠状动脉造影特点的影响。方法在分析203例冠心病合并2型糖尿病患者冠状动脉造影特点的基础上,按年龄、血脂及年龄与血脂分组进行分析。结果203例患者冠状动脉造影多为多支病变(≥3支比<3支为59.1%比40.9%,P<0.01)且血管狭窄程度高(≥75%比<75%为66%比34%,P<0.001)。≥60岁组4支血管病变比例高于<60岁组,而≥60岁组单支血管病变比例低于<60岁组。并且≥60岁组左主干受累比例高于<60岁组;胆固醇异常组与胆固醇正常组相比,单支、双支、3支及4支血管病变、狭窄部位和狭窄程度的差异无统计学意义。年龄与血脂进行交叉分组对比分析,低脂高龄组病例数明显高于高脂低龄组(43%比20%,P<0.001),但低脂高龄组单支病变明显低于高脂低龄组(11%比32%,P<0.05),4支病变明显高于高脂低龄组(24%比7%,P<0.05)。结论胆固醇的降低不能改变冠心病合并2型糖尿病患者冠状动脉病变特征随增龄而改变的趋势。
关键词(KeyWords)： 冠状动脉疾病;糖尿病,非胰岛素依赖型;高脂血症;年龄因素
基金项目(Foundation): 山东省科技发展计划(2003—35)号
作者(Author): 宫建丽,李文华,孔香云,张秀洲,唐元升,高燕燕,朱兴雷
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