中国介入心脏病学杂志

1998, (04) 183

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REDUCTION IN QT INTERVAL DISPERSION BY SUCCESSFUL CORONARY ANGIOPLASTY IN UNSTABLE ANGINA OR MYOCARDIAL INFACTION
REDUCTION IN QT INTERVAL DISPERSION BY SUCCESSFUL CORONARY ANGIOPLASTY IN UNSTABLE ANGINA OR MYOCARDIAL INFACTION

摘要(Abstract):

<正> Increases of QTc interval diapersion has been reported to be amarker for ischemia.The effects of coronary artery revascularizationon QTc dispersion have not been previously reported.We studiedOTcd in 34 patients with a mean age of 55 years(range 31-72)withcoronary artery disease who underwent successful,uncomplicatedcoronary angioplasty(PTCA).We analysed 12-lead ECGs recordedbefore,1 day and a week after the PTCA.QT intervals were mea-sured by an observer who was blinded to the time the ECG wasrecorded,and to all other clinical information.QT intervals were cor-rected using Bazett's formula.QTc interval dispersion was calculatedas the difference between the maximum and minimum of the 12-lead EKG QTc interval.The QTc dispersion in a day(35±13)and(34±13)a week after PTCA was significant less reductive than theQTc dispersion(64±16),before PTCA(P<0.05).Successful reves-cularization by PTCA results in a significant reduction in QTc inter-val dispersion which persists over time.It may be a mechanism ofbenefit of PTCA therapy.Whether this measurement would predictrestenosis in such patients requires further study.

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