迈向病理生物学导向下抗血小板治疗——解读美国心脏病学会2021年冠心病抗血小板治疗临床研究Towards antiplatelet therapy guided by pathobiology——Highlights of the American College of Cardiology 2021 antiplatelet therapy clinical studies for coronary artery diseases
颜红兵,余小平,霍勇
摘要(Abstract):
TALOS-AMI研究、HOST-EXAM研究和TAILOR-PCI延长期研究实际上是病理生物学导向下个体化抗血小板治疗的具体体现。临床实践中应对患者进行全面的病理生物学评价,确定实施降级治疗策略的时机,并且酌情动态调整。单药抗血小板治疗本质上属于降级治疗策略范畴,其实施也应遵循降级治疗策略原则。目前的循证医学证据不支持常规检测基因类型来指导选择抗血小板治疗。
关键词(KeyWords): 冠心病;双联抗血小板治疗;病理生物学
基金项目(Foundation): 深圳市医学重点学科(2020—2024年):心血管内科(SZXK001);; 深圳市“医疗卫生三名工程”:中国医学科学院阜外医院颜红兵教授急性冠状动脉综合征诊治团队(SZSM201911017)
作者(Author): 颜红兵,余小平,霍勇
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