曹成富,马玉良,李琪,刘健,赵红,卢明瑜,王伟民

• 1:北京大学人民医院心内科

摘要(Abstract)：

目的采用光学相干断层成像(OCT)证实冠状动脉斑块旋磨术对血小板激活的影响。方法连续纳入2019年7月至2019年12月于北京大学人民医院行OCT指导行冠状动脉斑块旋磨治疗的患者20例,分别在旋磨前、后行OCT检查。结果 20例患者中14例旋磨头直径为1.5 mm。20例患者平均旋磨速度为(15.2±0.4)×10~4 r/min,旋磨次数为(5.3±2.1)次,平均总旋磨时间为(49.5±8.1)s。其中有1例在旋磨后出现无复流现象。所有患者旋磨后行OCT检查,靶病变均出现血小板聚集现象(白色血栓),平均出现(7.2±4.4)个白血栓,尺寸为(0.5±0.3)mm。Pearson相关分析显示,血小板聚集的负荷大小与旋磨头直径(r=0.575, P=0.040)和总旋磨时间(r=0.599, P=0.031)相关。结论采用OCT证实,冠状动脉斑块旋磨术中可以引起血小板聚集,血小板聚集负荷与旋磨头大小和总旋磨时间相关。

关键词(KeyWords)： 钙化病变;冠状动脉斑块旋磨术;血小板聚集;光学相干断层成像

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金（81800316）

作者(Author): 曹成富,马玉良,李琪,刘健,赵红,卢明瑜,王伟民

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