氧化修饰低密度脂蛋白和血管内皮损伤
徐雅琴,张钧华,唐朝枢
摘要(Abstract)：
关键词(KeyWords)：
基金项目(Foundation):
作者(Author): 徐雅琴,张钧华,唐朝枢
参考文献(References)：
- 1 Witztum JI, DanielSteinberg. Role ofoxidized low den-sity lipoproteins in atherogenesis. JClin Invest, 1991,88:1785-1792.
- 2 刘乃丰.氧化低密度脂蛋白在动脉粥样硬化发生中的作用.中国病理生理杂志,1994,10:104-105.
- 3 王小东,周玫,陈瑗,等.高密度脂蛋白对氧化修饰的低密度脂蛋白损伤内皮细胞的防护作用. 中华医学杂志,1994,74:567-568.
- 4 Zhao B,Zhang Y, Lin B,etal.Endothelialcellsinjuredby oxidized low density lipoproteins. Am JHem atol,1995,49:250-252.
- 5 BoissonneaultGA, Wang Y, Chung BH, etal. Oxidizedlow density lipoproteins delay endothelial wound heal-ing: lack ofeffectofvitam in E. Ann NutrMetab, 1995,39:1-8.
- 6 Suc I, Escargueil-Blanc-I, Troly-M, etal. High densitylipoproteins and apo-aprevent cell death of endothelialcells induced by oxidized low density lipoproteins. Arte-riosclerosisThrom b Vasc Biol, 1997,17:2158-2166.
- 7 Seelos C, Gm einer-B, Kapiotis-S, et al. Oxidized lowdensity lipoproteins triggers program m ed death of en-dothelialcells. Biochem MolBiolInt, 1997, 42:1015-1022.
- 8 Dim m eler SF, Haendeler JD, Galle Jet al. Oxidizedlow-density lipoprotein induces apoptosis of hum an en-dothelial cells by activation of CPP32-like proteases.Circulation, 1997,95:1760-1763.
- 9 Chin JH, Azhar S, Hoffm an BB. Inactivation of en-dothelialderived relaxing factorby oxidized lipoproteins.JClin Invest, 1992,89:10-18.
- 10 Tanner FC, NellG, BoulangerCM, etal. Oxidized lowdensity lipoproteinsinhibitrelaxation ofporcinecoronaryarterries: roleofscavengerreceptorand endothelium -de-rived nitric oxide. Circulation, 1991,83:2012-2020.
- 11 Chen L, Liang B, FrooseDE, etal. Oxidized low densi-ty lipoproteinsin norm aland hyperlipidem icpatients: ef-fectof lysophosphatiolylcholine com position on vascularrelaxation. JLipid Res, 1997,38:546-553.
- 12 Fogliatto G, Musanti R, Pirillo A, et al. Oxidizedlipoproteins induce long-lastine inhibitior of nitric oxidesynthase from Am urineendothelium acellline. JCardio-vascRisk, 1995,2:123-130.
- 13 Hirata K, MikiN, Kuroda Y, etal. Low concentrationof oxidized low density lipoproteins and lysophos-phatidylcholine upregulate constitutive nitric oxide syn-thase m RNA expression in bovine aortic endothelialcells. Circ Res, 1995,76:958-962.
- 14 HorioJ,Kohno M, Yasunan K,etal. Stim ulation ofen-dothelin-1 release by low density lipoproteinsand VLDLin cultured hum an endothelial cells. Atherosclerosis,1993,101:185-190.
- 15 He Y, Kwan WC, SteinbrecherUP,etal.Effectsofoxi-dized low density lipoproteins on endothelin secretion bycultured endothelial cells and MQ. Atherosclerosis,1996,119:107-118.
- 16 Cox DA, Cohen ML. Selective enhancem ent of 5-hy-droxytryptam ine-induced contraction ofporcinecoronaryartery by oxidized low density lipoproteins. JPharm acolExp Ther, 1996,276:1095-1103.
- 17 Weber C, Erl W, Weber PC, et al. Enhancem ent ofm onocyte adhesion to endothelial cells by oxidized lowdensity lipoproteins is m ediated by activation ofCD11b.Biochem Biophys Res Com m un, 1995,206:621-628.
- 18 Am berger A, Maczek C, Jurgenc G, et al. Co-expres-sion ofTCAM-1, ECAM-1 and Hsp60 in hum an arterialand venous endothelialcells through degradation of thelipoprotein in lysosom es. CellStress Chaperones, 1997,2:94-103.
- 19 Drake IA, HannaniK, FeiHH, et al. Minim ally oxi-dized low density lipoproteins induces tissue factor ex-pression in cultured hum an endothelial cells. Am JPathol, 1991,138:601-607.
- 20 Wilson BD,PitasRE, RodeersGM,etal. Regulation ofendothelialcells protein C activation by native and oxi-dized low density lipoproteins. Sem in Throm b Hem ost,1992,18:11-17.
- 21 IshiiH, KizakiK, Horie S, etal. Oxidized low densitylipoproteins reduces throm bom odulin transcription incultured hum an endothelialcells through ofthe lipopro-tein in lysosomes. JBiolChem , 1996,271:8458-8465.
- 22 MougenotN, Lesnik P, Ram irez-GilJF, etal. Effectofthe oxidation state of low density lipoproteins on them odulation of arterial vasom otor response in vitro.Atherosclerosis, 1997,133:183-192