治疗心力衰竭的新型器械——心房分流器的研究进展
尚小珂,陈澍,董念国,钟良,王斌,朱达,宋光远,廖曼,张长东
摘要(Abstract):
<正>心力衰竭是各种慢性结构性或非结构性心脏病发展到后期的共同表现。美国现有620万例心力衰竭患者群体,并且由于人口老龄化的不断进展发病率持续增加[1]。针对这些患者的不良预后,已经有许多控制心力衰竭进展和提高心力衰竭患者生存率的治疗方法。近几年,在指南的规范药物治疗下开始出现一些辅助器械治疗(例如心脏再同步疗法、植入式监测器、心室辅助装置)和心脏移植等[2]。尽管如此,还需要进一步研发新的心力衰竭器械,以解决目前仍然较高的患者死亡率(高危亚组每年20%~25%)和大量的心力衰竭住院率(美国每年>100万人次)[1]。心房分流术是一种治疗心力衰竭的新方法。对于许多患者
关键词(KeyWords): 心力衰竭;房间隔;分流器;左心房压力;左心前负荷
基金项目(Foundation): 国家自然科学基金(81570325);; 湖北省卫健委创新基金(WJ2019M173);; 国家重点研发计划(2016YFA0101100)
作者(Author): 尚小珂,陈澍,董念国,钟良,王斌,朱达,宋光远,廖曼,张长东
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