cTnI定量检测对不稳定性心绞痛患者冠脉病变程度和预后的判断价值The value of serum cardiac troponin I with the severity and extent of coronary lesions and the prognosis in unstable angina pectoris
石奇松,王喜卓,俞红,石仲仁,刘秉强,许金鹏,杨菁
摘要(Abstract)：
目的 探讨不稳定性心绞痛 (UAP)患者cTnI定量检测同冠脉病变数量、程度和预后之间的关系。方法 不稳定性心绞痛患者 6 8例 ,采用美国DPC公司全自动化学发光免疫检测系统及试剂进行血清cTnI定量检测、CK MB质量试验。并行冠脉造影术。随访观察 30天后心脏事件的发生。结果 6 8例UAP患者中 ,A组 2 6例 (占 38 2 % ) ,cTnI≥ 0 4ng/ml。B组 42例 (占 6 1 8% ) ,cTnI <0 4ng/ml。同步测定CK MB质量 ,二组间差异无显著性。A组中C型病变、三支病变、左主干受累和高度狭窄 2 0例 (占 76 9% ) ,明显高于B组 9例 (占 2 1 4% ,P <0 0 5 )。A组Braunwald分级ⅢA或ⅢB者 2 3例 (占 88 5 % ) ,B组仅 3例 (占 7 1% ) ,明显高于B组 (P <0 0 0 1)。A组 30天内发生心脏事件 14例(占 5 3 8% ) ,明显高于B组 4例 (占 9 5 % ,P <0 0 1)。结论 化学发光免疫分析法cTnI定量检测同冠状动脉病变数量及严重程度、临床Braunwald分级有密切关系。并对判断不稳定性心绞痛患者预后有一定的预测价值
关键词(KeyWords)： 肌钙蛋白;不稳定性心绞痛;冠状动脉造影后预后;冠状动脉造影
基金项目(Foundation):
作者(Author): 石奇松,王喜卓,俞红,石仲仁,刘秉强,许金鹏,杨菁
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