大鼠离体心脏急性冬眠心肌模型的建立Acute hibernating myocardium in isolated rat heart
邱原刚,张钧华,唐朝枢,李大元,陈健,邵耕
摘要(Abstract)：
利用悬浮人类红血球的改良K-H液灌流大鼠离体等容收缩心脏,建立了急性冬眠心肌模型,缺血期间冠状动脉流量下降80%.结果表明,缺血30分钟时,左室内收缩峰压、dp/dt max、—dp/dt max分别降到对照组的44%、33%和26%(P均<0.05),缺血期间保持恒定,再灌注30分钟完全恢复.缺血90分钟,心肌ATP、磷酸肌酸(Crp)及糖原含量明显降低(P均
关键词(KeyWords)：
心肌缺血;急性冬眠心肌;心功能;高能磷酸化合物
基金项目(Foundation):
作者(Author):
邱原刚,张钧华,唐朝枢,李大元,陈健,邵耕
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