邱林,朱航,马为,张玉顺

• 1:北京大学第一医院心内科
• 2:中国人民解放军总医院第六医学中心心血管病医学部结构性心脏病科
• 3:北京大学第一医院心血管疾病研究所超声心动图中心实验室
• 4:西安交通大学第一附属医院结构性心脏病科

摘要(Abstract)：

卵圆孔未闭（PFO）是一种在人群中患病率较高的先天性心脏病，既往研究已明确其与脑卒中之间的关联，并认可封堵治疗对于PFO相关脑卒中的意义。近年来，关于PFO相关疾病的研究逐渐增多，认识进一步加深，同时国内PFO封堵治疗的例数也增长明显。本文盘点了2023年度PFO领域最新研究进展，主要包括PFO相关疾病谱的扩展（癫痫、不明原因晕厥等），发病机制的探究以及风险评估的手段；针对PFO封堵治疗，本文介绍了关于封堵效果与预后的最新研究结果，以及封堵治疗与心房颤动之间关系。国内在PFO封堵新器械的研发上一直处于领先地位，本文也对该方面的最新成果进行了介绍。

关键词(KeyWords)： 卵圆孔未闭;卵圆孔未闭相关疾病;发病机制;封堵;预后

Abstract:

Keywords:

基金项目(Foundation): 国家重点研发计划项目（2021YFC2501106）

作者(Author): 邱林,朱航,马为,张玉顺

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