徐玲,张瑞涛,杨林承,王雅亭,徐东晓,童素梅,朱丹,唐熠达

• 1:北京大学第三医院心内科血管医学研究所国家卫生健康委心血管分子生物学与调节肽重点实验室分子心血管学教育部重点实验室心血管受体研究北京市重点实验室

摘要(Abstract)：

目的 探讨腰臀比等肥胖相关指标与冠状动脉病变的关系。方法 回顾性收集2020年10月至2021年4月北京大学第三医院心血管代谢门诊患者的临床资料，包括其肥胖相关参数及冠状动脉影像学结果，评价腰臀比等肥胖相关指标与冠状动脉病变严重程度的关系。结果 共纳入就诊于心血管代谢门诊患者342例，发现未合并冠状动脉病变的患者腰臀比高于合并冠状动脉病变者，但在冠心病患者中伴随冠状动脉病变支数增加，腰臀比有升高趋势（P=0.001）。后以残余SYNTAX评分作为冠状动脉遗留病变的评价指标，发现腰臀比（OR 2.507,95%CI 1.053～5.966,P=0.014）、腰围（OR2.273,95%CI 1.033～5.378,P=0.024）、糖尿病史（OR 1.824,95%CI 1.099～3.027,P=0.002）与残余SYNTAX评分独立相关。结论 不同冠状动脉病变支数受试者腰臀比分布存在差异，冠心病患者中冠状动脉病变支数与腰臀比独立相关，同时腰臀比是冠心病患者冠状动脉残余病变严重程度的独立危险因素。上述结果为进一步明确肥胖相关参数与冠状动脉病变之间的关系提供了依据。

关键词(KeyWords)： 冠状动脉性心脏病;腰臀比;残余SYNTAX评分

Abstract:

Keywords:

基金项目(Foundation): 朱丹,北大医学青年科技创新培育基金（BMU2022PY026）

作者(Author): 徐玲,张瑞涛,杨林承,王雅亭,徐东晓,童素梅,朱丹,唐熠达

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