经皮二尖瓣球囊成形术治疗二尖瓣狭窄伴瓣膜明显畸形的临床疗效观察Percutaueous balloon mitral valvuloplasty for mitral stenosis patients with severe mitral valve deformity: clinical outcome and safety
舒茂琴,何国祥,宋治远,王敏中,司良毅
摘要(Abstract)：
分析经皮二尖瓣球囊扩张术（PBMV）治疗二尖瓣狭窄伴严重瓣膜畸形（超声评分≥10分）的临床疗效和安全性。本组共32例，男12例，女20例，平均48岁。手术成功率100％。术后二尖瓣口面积（MVA）从0．91±0．12cm2增加到1．48±0．21cm2（P＜0．05），平均左房压力从23．1±5．2mmHg降到16．8±4．9mmHg，平均肺动脉压从48．9±12．8降到了31．2±14．0mmHg（P＜0．05）。本组手术前后二尖瓣反流程度无明显增加，出院时仅2例发生了明显的二尖瓣反流，无心包填塞、栓塞和死亡，即手术并发症为6．3％。有84％的患者术后心功能改善，心功能恶化者占6．3％。结论：PBMV治疗二尖瓣狭窄伴严重瓣膜畸形的手术成功率高，并发症少，虽对血流动力学的改善不完全，但能改善绝大多数患者的临床症状。
关键词(KeyWords)： 二尖瓣狭窄;球囊扩张术
基金项目(Foundation):
作者(Author): 舒茂琴,何国祥,宋治远,王敏中,司良毅
参考文献(References)：
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