“正常”冠状动脉慢血流现象相关因素分析Analysis of correlation factors of slow coronary flow
龚艳君,洪涛,李建平,张启华,赵文岭,霍勇
摘要(Abstract):
目的初步探讨可能与冠状动脉慢血流现象有关的危险因素。方法回顾性分析2005年1月至2006年12月因怀疑冠心病于北京大学第一医院行冠状动脉造影显示心外膜主要冠状动脉无明显病变的病例86例。通过TIMI计帧法计数各支冠状动脉的TIMI帧数。冠状动脉平均TIMI帧数大于27帧定义为慢血流,将患者分为慢血流组(n=34)和对照组(n=52)。应用t检验和卡方检验比较两组间各项临床指标的差异,并采用多元logistic回归分析对影响慢血流的各因素进行分析。结果两组患者性别、年龄,高血压病、糖尿病、高脂血症、吸烟者所占比例,白细胞计数、血小板计数、空腹血糖、甘油三酯、总胆固醇、LDL-C、HDL-C水平的差异无统计学意义(P>0.05),而慢血流组与对照组相比,体重指数(26.9±3.2kg/m2比24.9±2.9kg/m2,P<0.05)、血红蛋白(139.8±14.8g/L比132.4±15.1g/L,P<0.05)均高于后者。多元logistic回归分析表明,只有体重指数是影响慢血流发生的危险因素(OR1.227,95%CI1.051~1.431,P=0.009)。结论体重指数升高可能参与慢血流发生的病理生理过程。
关键词(KeyWords): 冠状血管造影术;血流速度;人体质量指数
基金项目(Foundation):
作者(Author): 龚艳君,洪涛,李建平,张启华,赵文岭,霍勇
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