导管溶栓治疗肺栓塞的研究The latest development of catheter-directed thrombolysis for patients with pulmonary embolism
孙冰,郭蕊,陈蕊蕊,薛凯
摘要(Abstract):
肺栓塞是一种死亡率高且会引起远期不良预后的心血管疾病。长期以来,抗凝和全身溶栓是治疗肺栓塞的主要手段。近年来,导管溶栓被越来越多地应用到了肺栓塞的治疗当中。与单独抗凝相比,导管溶栓可以更快、更有效地降低肺动脉压力、改善右心室功能;与全身溶栓相比,导管溶栓可以减少出血发生率,应用更安全,使用范围更广。然而由于相关临床试验数据的缺乏,相关指南对导管溶栓都只是Ⅱ类推荐。本文将对导管溶栓治疗肺栓塞的最新研究进行回顾,以期找出最合理的治疗使用方案。
关键词(KeyWords): 肺栓塞;导管溶栓;抗凝
基金项目(Foundation):
作者(Author): 孙冰,郭蕊,陈蕊蕊,薛凯
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