张腊婷,王晓庆,韩琳,梁新慧,贾瑶,高丽娟,姜雪

• 1:陕西中医药大学护理学院
• 2:空军军医大学唐都医院神经外科
• 3:陕西中医药大学附属医院感染管理办公室

摘要(Abstract)：

目的 应用Meta分析方法探讨颈动脉支架置入术后血流动力学不稳定的危险因素。方法 检索PubMed、ProQuest、ScienceDirect、Embase、CochraneLibrary、Webof Science、中国知网、万方数据、维普、中国生物医学文献数据库10个数据库。检索时限从建库至2024年2月2日，采用Stata 16.0统计软件进行Meta分析。结果 共纳入27项研究，4 199例受试者，22项影响因素。研究显示颈动脉支架置入术后出现血流动力学不稳定的发生率为37.4%(95%CI 30.3%～44.8%),Meta分析确定年龄>60岁（P<0.001）、高血压（P<0.001）、钙化斑块（P<0.001）、狭窄程度>70%(P=0.008)、偏心性斑块（P=0.002）、最大狭窄到颈动脉分叉的距离≤10 mm(P<0.001)、狭窄累及球部或分叉部（P<0.001）、球囊后扩张（P=0.003）、开环支架（P<0.001）、扩张球囊直径≥5 mm(P=0.002)、重复球囊扩张（P=0.011）及球囊扩张压力≥8 atm(P<0.001)是颈动脉支架置入术患者术中及术后血流动力学不稳定的危险因素。他汀类药物的使用（P<0.001）是保护因素。结论 临床工作的医务人员应在术前对患者的情况进行评估，识别可能导致血流动力学不稳定的危险因素，避免对已经处于高危状态的患者进行不必要的术中刺激。减少颈动脉狭窄患者术后临床并发症，提高患者康复能力。

关键词(KeyWords)： 颈动脉支架置入;血流动力学不稳定;危险因素;Meta分析

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 张腊婷,王晓庆,韩琳,梁新慧,贾瑶,高丽娟,姜雪

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