林立志,尹晓荣,崔璐,申程,王明皓,房芳,杜艳艳,孙传峰,曹勇

• 1:济宁医学院临床医学院
• 2:济宁市心血管病疾病诊疗重点实验室
• 3:济宁医学院附属医院心内科冠心病二病区

摘要(Abstract)：

目的 评估经皮冠状动脉腔内冲击波球囊导管成形术（即血管内碎石术，IVL治疗冠状动脉钙化病变的安全性和有效性。方法 回顾性分析2023年1月至2023年7月于济宁医学院附属医院在血管内成像技术指导下，使用IVL或切割球囊（CB）治疗冠状动脉钙化病变的患者53例（IVL组18例，CB组35例）。通过比较两组的基线资料、临床成功率，住院期间和手术后1个月随访患者主要不良心血管事件（MACE）和1个月内因心血管事件再入院情况，评估IVL治疗冠状动脉钙化病变的安全性和有效性。结果 IVL组和CB组的临床成功率（100.0%比100.0%,P>0.999）相同，病变最小管腔面积[（1.7±0.4）mm~2比（1.7±0.5）mm~2,P=0.628]相似，但病变长度[（28.4±9.6）mm比（20.9±8.6）mm,P=0.008]、残余狭窄[（1.7±1.7）%比（6.9±2.0）%,P=0.049]差异均有统计学意义。手术过程中，均无血栓、血管急性闭塞等急性并发症发生。两组住院期间和随访1个月时均无MACE发生（0比0,P>0.999）,CB组有3例患者因心绞痛再入院治疗（0比8.6%,P=0.543），但差异无统计学意义。结论 IVL治疗冠状动脉钙化病变是安全、有效的。

关键词(KeyWords)： 血管内碎石术;切割球囊;血管内成像;冠状动脉钙化

Abstract:

Keywords:

基金项目(Foundation): 济宁市重点研发计划项目（2022YXNS022）;; 主诊医师团队专项临床研究计划项目（ZZTD-2022-002）

作者(Author): 林立志,尹晓荣,崔璐,申程,王明皓,房芳,杜艳艳,孙传峰,曹勇

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