王群山,汪智全,孙健,冯向飞,刘博,张澎湃,王君,张睿,李毅刚

• 1:上海交通大学医学院附属新华医院心内科

摘要(Abstract)：

目的探讨经导管射频消融术治疗心房颤动患者并发心脏压塞与HAS-BLED评分的相关性。方法收集上海交通大学医学院附属新华医院心内科2004年1月至2015年9月行经导管射频消融术治疗心房颤动患者的临床资料,筛选出其中并发心脏压塞的患者,采用病例-对照研究方法,按1∶1匹配非心脏压塞患者。回顾性分析患者的基本资料,并进行多因素回归分析明确心房颤动并发心脏压塞的相关危险因素。结果心房颤动经导管射频消融术的患者中共有38例并发心脏压塞,其中21例为术中急性心脏压塞,17例为术后迟发性心脏压塞,行紧急心包穿刺和引流后均明显好转并痊愈出院。心脏压塞组和非心脏压塞组患者的HAS-BLED评分[(2.03±1.10)分比(1.42±0.92)分,P=0.011]和冠心病占比[12例(31.6%)比5例(13.2%),P=0.000]的差异均有统计学意义。Logistic多因素回归分析显示,HAS-BLED评分较高是经导管射频消融术治疗心房颤动并发心脏压塞的独立危险因素[Exp(B)=1.893,P=0.021];而是否合并糖尿病(P=0.266)、冠心病(P=0.195)、心功能不全(P=0.149)及心房颤动类型(P=0.537)与心房颤动经导管射频消融术并发心脏压塞无显著相关性。结论紧急心包穿刺、引流是处理心房颤动经导管射频消融术并发心脏压塞的有效手段。HAS-BLED评分较高是经导管射频消融术治疗心房颤动并发心脏压塞的独立危险因素。

关键词(KeyWords)： 心房颤动;经导管射频消融术;心脏压塞;HAS-BLED评分

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金面上项目(81270259);; 青年科学基金项目(81200603)

作者(Author): 王群山,汪智全,孙健,冯向飞,刘博,张澎湃,王君,张睿,李毅刚

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