西罗莫司洗脱支架与裸金属支架治疗冠心病多支病变的远期安全性比较Comparison of Long-Term Safety of Coronary Sirolimus-Eluting Stent with Bare Metal stent implantation in patients with multivessel coronary disease
高迎春,马长生,聂绍平,杜昕,吕强,张崟,康俊平,刘新民,贺立群,阙斌,董建增,刘晓慧,吴学思
摘要(Abstract)：
目的观察多支冠状动脉病变使用西罗莫司洗脱支架行血运重建的远期临床安全性。方法单中心回顾性病历复习,入选冠状动脉造影显示2支、3支冠状动脉病变或左主干病变的患者562例。根据置入支架的不同,分为药物洗脱支架(SES)组(251例)、裸金属支架(BMS)组(311例)。对两组患者出院后死亡和AMI事件进行随访分析。结果中位随访时间为19.4个月,随访率92.9%。血运重建1年后心性死亡SES组3例,BMS组1例;非致死性心肌梗死每组2例。上述事件的发生率两组间差异无统计学意义(2.3%比1.1%,P=NS)。Kaplan-Meier方法分析显示,出院后无心性死亡和非致死性心肌梗死事件生存率两组间差异无统计学意义(97.3%比97.2%,P=0.951)。结论研究显示,多支冠状动脉病变西罗莫司洗脱支架置入治疗与裸金属支架比较,远期心性死亡和AMI事件的发生率相似,提示远期支架内血栓形成率不增加。
关键词(KeyWords)： 冠状动脉疾病;支架;冠状动脉血栓形成
基金项目(Foundation):
作者(Author): 高迎春,马长生,聂绍平,杜昕,吕强,张崟,康俊平,刘新民,贺立群,阙斌,董建增,刘晓慧,吴学思
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