可注射水凝胶在慢性心力衰竭治疗中的前景与挑战The prospect and challenges of injectable hydrogel in the treatment of chronic heart failure
李树成,郭炳辰,高殿钰,王博,涂应锋
摘要(Abstract):
心力衰竭是心血管疾病最主要的死亡原因,也是大多数心血管疾病的终末共同表现,全球约超过六千万人深受其影响。心脏移植目前仍是心力衰竭患者的治疗“金标准”,心力衰竭患者在遵循基础药物治疗的情况下可以改善生活质量,延长生存时间。但由于心力衰竭的复杂机制以及众多并发症,常规的心力衰竭治疗策略在临床工作中的局限性被逐渐放大。近年来,介入治疗作为一种新兴的心力衰竭的治疗手段,受到人们的关注并取得重大突破,为心力衰竭患者带来新的希望。其中,可注射水凝胶由于其微创性和有效输送治疗药物的能力,在生物医学领域的应用受到了极大的关注。在慢性心力衰竭领域,可注射水凝胶主要应用于组织再生、药物输送和免疫治疗等。本文主要阐述可注射水凝胶在心力衰竭治疗领域的应用及研究进展。
关键词(KeyWords): 心力衰竭;介入治疗;可注射水凝胶
基金项目(Foundation): 哈尔滨医科大学附属第一医院科研创新基金项目(2024M32)
作者(Author): 李树成,郭炳辰,高殿钰,王博,涂应锋
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