腺苷及腺苷受体在预处理中的作用
陈健,张钧华
摘要(Abstract):
<正>缺血预处理(ischemic preconditioning)这一概念首先由Murry等人提出,它是指心肌在经受短暂缺血后,能在随后的长时间缺血中延迟并减轻心肌的损伤,他们将这种心肌保护效应命名为缺血预处理,现一般简称为预处理(preconditioning).此后,世界许多实验室在这方面做了大量研究,表明预处理对各种缺血/再灌注损伤具有显著的保护作用,包括缺血坏死、缺血后功能异常、缺血所致心律失常以及再灌注心律失常,而其确切的机制至今尚未明了.
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基金项目(Foundation):
作者(Author): 陈健,张钧华
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