赵林,张宇晨,郭成军,王雷

• 1:首都医科大学附属北京安贞医院心内科
• 2:首都医科大学附属北京友谊医院心内科

摘要(Abstract)：

目的评价入院估算的肾小球滤过率(eGFR)对接受急诊PCI治疗的ST段抬高型心肌梗死(STEMI)患者冠状动脉血流和预后的影响。方法回顾性收集因STEMI而在12h内接受急诊PCI治疗的患者495例。根据患者入院时eGFR分为两组:eGFR≥60ml·min-1·1.73m-2组和eGFR<60ml·min-1·1.73m-2组。比较两组患者的临床资料、介入手术资料和1年随访资料。结果 eGFR<60ml·min-1·1.73m-2组96例,eGFR≥60ml·min-1·1.73m-2组399例。与eGFR≥60ml·min-1·1.73m-2组相比,eGFR<60ml·min-1·1.73m-2组患者入院时年龄更大,男性患者更多,多支病变患者更多,高血压患者更多,既往心肌梗死病史患者增加,入院及出院eGFR更低,Killip's分级更高。eGFR<60ml·min-1·1.73m-2组校正TIMI计帧数比eGFR≥60ml·min-1·1.73m-2组更高,并且TIMI心肌灌注分级(TMP)0～1级患者更多(5.0%比14.6%)。入院eGFR<60ml·min-1·1.73m-2是接受急诊PCI的STEMI患者心肌灌注不良(校正相对危险度OR=3.95,95%CI:1.23～6.89)和1年死亡率(校正OR=1.48,95%CI:1.21～2.97)的独立预测因子。结论入院eGFR下降与急诊PCI治疗的STEMI患者心肌灌注不良和预后不良相关。

关键词(KeyWords)： 心肌梗死;血管成形术,经腔,经皮冠状动脉;肾功能不全

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 赵林,张宇晨,郭成军,王雷

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