急性冠状动脉综合征合并慢性肾病患者介入术后双联抗血小板治疗的研究进展Antiplatelet therapy for patients with acute coronary syndrome and chronic kidney disease after percutaneous coronary intervention
崔静达,韩江莉
摘要(Abstract):
阿司匹林联合P2Y12受体抑制剂是预防急性冠状动脉综合征(ACS)经皮冠状动脉介入治疗后支架内血栓形成及全身动脉粥样硬化血栓事件的标准双联抗血小板治疗方案。ACS合并慢性肾病(CKD)患者血栓风险和出血发生率更高,因此,确定这一人群的最佳抗血小板药物治疗策略至关重要。既往大多数临床试验将晚期CKD患者排除在外,因而临床医师对这部分患者的抗血小板治疗策略缺乏循证医学证据。现综述ACS合并CKD患者抗血小板治疗研究进展,以期为临床医师面临此类患者时选择合适的抗血小板治疗策略提供借鉴。
关键词(KeyWords): 急性冠状动脉综合征;慢性肾病;抗血小板治疗
基金项目(Foundation):
作者(Author): 崔静达,韩江莉
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