车波,徐承义,徐文杰,鄢华,宋丹

• 1:武汉亚洲心脏病医院心内科

摘要(Abstract)：

经导管主动脉瓣置换术（TAVR）已成为国内外指南推荐治疗老年主动脉瓣狭窄（AS）的一线治疗方案，也适用于AS合并不同严重程度主动脉瓣反流的患者，但在单纯主动脉瓣反流（PAR）中却不做常规推荐，传统外科主动脉瓣置换术仍然是治疗PAR的金标准。外科手术禁忌或高危PAR患者，常放弃外科手术治疗，选择保守治疗，而后者的死亡率更高。经股动脉TAVR(TF-TAVR)为其提供了一种替代治疗方案，尽管仍面临手术技术要求高、缺乏针对PAR的瓣膜系统和术后长期随访数据等挑战，但随着TAVR技术经验积累、新一代瓣膜系统的发展及长期随访数据的反馈，TF-TAVR治疗PAR逐渐被证实是一种安全、可行的外科手术替代治疗方式，本文对TF-TAVR治疗PAR实施要点、临床研究现状以及未来的发展进行综述。

关键词(KeyWords)： 经导管主动脉瓣置换术;经股动脉;单纯主动脉瓣反流;经导管心脏瓣膜;主动脉瓣狭窄

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 车波,徐承义,徐文杰,鄢华,宋丹

参考文献(References)：

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