慢性完全闭塞病变血运重建后围术期心肌梗死发生率及危险因素分析The prevalence and risk factors for periprocedural myocardial infarction after revascularization in chronic total occlusion
刘严慈,彭红玉,柳景华,李文铮,吴铮,赵东晖,程子超
摘要(Abstract):
目的 采用慢性完全闭塞病变学术联盟(CTO-ARC)专家共识定义,按照CTOARC围术期心肌梗死(PMI)标准,评价慢性完全闭塞(CTO)病变行经皮冠状动脉介入治疗(PCI)PMI的发生率,并对相关危险因素进行分析。方法 根据CTO-ARC标准,回顾性分析首都医科大学附属北京安贞医院冠心病中心自2019年1—6月所有通过PCI成功完成血运重建的CTO病变患者的临床基线特征、造影结果以及手术操作特点,应用多因素Logistic回归分析识别PMI的独立危险因素。结果 纳入通过PCI成功完成血运重建的CTO病变415例,PMI发生率4.8%。经多因素Logistic回归分析,供血血管闭塞(OR 48.818,95%CI 2.365~1 007.888,P=0.012)、边支血管损伤(OR 20.332,95%CI 4.439~93.132,P<0.01)、术后心肌梗死溶栓治疗试验(TIMI)血流分级<Ⅲ级(OR 33.310,95%CI6.209~178.689,P<0.01)及支架长度(OR 1.020,95%CI1.005~1.035,P=0.011)与CTO病变血运重建后PMI密切相关。结论 供血血管闭塞、边支血管损伤、术后TIMI血流分级<Ⅲ级及支架长度与CTO病变血运重建后PMI密切相关。
关键词(KeyWords): 慢性完全闭塞病变;经皮冠状动脉介入治疗;围术期心肌梗死
基金项目(Foundation):
作者(Author): 刘严慈,彭红玉,柳景华,李文铮,吴铮,赵东晖,程子超
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