王奕丹,代建南,房超,于波

• 1:哈尔滨医科大学第二附属医院心内科国家教育部心肌缺血重点实验室

摘要(Abstract)：

吸烟与急性ST段抬高型心肌梗死(STEMI)的风险增加密切相关,它影响着冠状动脉粥样硬化的各个阶段。STEMI在冠状动脉内血栓完全阻塞管腔时发生,除典型症状以外,心电图会显示ST段抬高,此时应尽快行急诊经皮冠状动脉介入治疗(PCI),重症患者在急诊PCI术之前也可以进行溶栓治疗。STEMI患者的短期预后优于非STEMI患者,但在长期预后上两者无较大差异。与非吸烟者相比,吸烟的STEMI患者对PCI及药物治疗的反应可能不同。病理学、临床研究和影像学研究对吸烟这一危险因素导致的STEMI给予了高度关注,这也为吸烟患者的治疗提供了新思路。本文将从吸烟及STEMI在国内外的流行病特点、吸烟在冠状动脉粥样硬化形成中的影响和作用、吸烟对STEMI发生的影响和作用、吸烟对STEMI患者预后的影响这四方面进行综述。

关键词(KeyWords)： 吸烟;急性ST段抬高型心肌梗死;冠状动脉粥样硬化斑块

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(81801861);; 中国博士后科学基金(2018M630373、2019T120283);; 黑龙江博士后基金(LBHTZ15)

作者(Author): 王奕丹,代建南,房超,于波

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