董晓雪,杨栋,王汉斌,张邢炜

• 1:杭州师范大学医学院
• 2:杭州师范大学附属医院心内科

摘要(Abstract)：

<正>左心耳(left atrial appendage,LAA)是左心房的附属结构,是心源性血栓的主要来源。近年来,随着介入治疗器械及技术的发展,以及对LAA结构和功能认识的深入,经皮左心耳封堵术(percutaneous closure of left atrial appendage,PCLAA)因在预防心房颤动(房颤)患者血栓栓塞并发症发生中呈现的安全性和有效性而备受青睐~[1-3]。但LAA的形

关键词(KeyWords)： 左心耳;封堵术;测量;三维重建

Abstract:

Keywords:

基金项目(Foundation): 国家级大学生创新创业训练计划项目(201510346013);; 浙江省大学生科技创新活动暨新苗人才计划项目(2015R423055)

作者(Author): 董晓雪,杨栋,王汉斌,张邢炜

参考文献(References)：

• [1]Landmesser U,Holmes DR Jr.Left atrial appendage closure:a percutaneous transcatheter approach for stroke prevention in atrial fibrillation.Eur Heart J,2012,33(6):698-704.
• [2]Alli O,Holmes D Jr.Evaluation of the WATCHMAN left atrial appendage closure device.Expert Rev Med Devices,2014,11(6):541-551.
• [3]Holmes DR Jr,Kar S,Price MJ,et al.Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy:the PREVAIL trial.J Am Coll Cardiol,2014,64(1):1-12.
• [4]De Backer O,Arnous S,Ihlemann N,et al.Percutaneous left atrial appendage occlusion for stroke prevention in atrial fibrillation:an update.Open Heart,2014,1(1):e000020.
• [5]Reddy VY,Doshi SK,Sievert H,et al.Percutaneous left atrial appendage closure for stroke prophylaxis in patients with atrial fibrillation:2.3-Year Follow-up of the PROTECT AF(Watchman Left Atrial Appendage System for Embolic Protection in Patients with Atrial Fibrillation)Trial.Circulation,2013,127(6):720-729.
• [6]Scowcroft AC,Lee S,Mant J.Thromboprophylaxis of elderly patients with AF in the UK:an analysis using the General Practice Research Database(GPRD)2000-2009.Heart,2013,99(2):127-132.
• [7]Proietti R,Joza J,Arensi A,et al.Novel nonpharmacologic approaches for stroke prevention in atrial fibrillation:results from clinical trials.Med Devices(Auckl),2015,8:103-114.
• [8]Camm AJ,Lip GY,De Caterina R,et al.2012 focused update of the ESC Guidelines for the management of atrial fibrillation:an update of 2010 ESC Guidelines for the management of the 2010ESC Guidelines for the management of atrial fibrillation.Developed with the special contribution of the European Heart Rhythm Association.Eur Heart J,2012,33(21):2719-2747.
• [9]January CT,Wann LS,Alpert JS,et al.2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation:Executive Summary:A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.Circulation,2014,130(23):2071-2104.
• [10]Koplay M,Erol C,Paksoy Y,et al.An investigation of the anatomical variations of left atrial appendage by multidetector computed tomographic coronary angiography.Eur J Radiol,2012,81(7):1575-1580.
• [11]Johri AM,Witzke C,Solis J,et al.Real-time three-dimensional transesophageal echocardiography in patients with secundum atrial septal defects:outcomes following transcatheter closure.J Am Soc Echoeardiogr,2011,24(4):431-437.
• [12]樊友启,杨倩,蒋峻,等.经导管左心耳封堵术预防房颤血栓栓塞.中华急诊医学杂志,2014,23(7):735-739.
• [13]Mbius-Winkler S,Sandri M,Mangner N,et al.The WATCHMAN left atrial appendage closure device for atrial fibrillation.J Vis Exp,2012,(60).
• [14]Nakajima H,Seo Y,Ishizu T,et al.Analysis of the left atrial appendage by three-dimensional transesophageal echocardiography.Am J Cardiol,2010,106(6):885-892.
• [15]Christiaens L,Varroud-Vial N,Ardilouze P,et al.Real threedimensional assessment of left atrial and left atrial appendage volumes by 64-slice spiral computed tomography in individuals with or without cardiovascular disease.Int J Cardiol,2010,140(2):189-196.
• [16]Lang RM,Tsang W,Weinert L,et al.Valvular heart disease:the value of 3-dimensional echocardiography.J Am Coll Cardiol,2011,58(19):1933-1944.
• [17]Jaguszewski M,Manes C,Puippe G,et al.Cardiac CT and echocardiographic evaluation of peri-device flow after percutaneous left atrial appendage closure using the AMPLATZER cardiac plug device.Catheter Cardiovasc Interv,2015,85(2):306-312.
• [18]姚焰,吴灵敏,侯炳波,等.经皮左心耳封堵术在心房颤动脑卒中高危患者应用.中华心律失常学杂志,2013,17(2):154-155.
• [19]刘晓伟,李彩英,于晨,等.256层螺旋CT左心耳定量测量的可重复性研究.中国临床医学影像杂志,2014,25(2):86-89.
• [20]You JH,Kang SG,Kim BM.A novel measurement technique for the design of fenestrated stent grafts:Comparison with threedimensional aorta models.Exp Clin Cardiol,2013,18(1):48-52.