西罗莫司洗脱支架(CypherTM)治疗支架内再狭窄Sirolimus-eluting stents for the treatment of in-stent restonosis
李忠红,衣为民,彭长农,龙娟,王丽丽
摘要(Abstract):
目的探讨CypherTM药物洗脱支架治疗支架内再狭窄的安全性和有效性。方法11例支架内再狭窄患者共置入CypherTM药物洗脱支架15枚,所有患者随访6个月,并于术后6个月复查冠状动脉造影。结果介入手术成功率100%,未发生与介入治疗相关的并发症。术后所有患者临床症状明显改善,6个月复查冠状动脉造影,无一例发生再狭窄。结论西罗莫司(雷帕霉素)洗脱支架治疗支架内再狭窄有很强的安全性、有效性。
关键词(KeyWords): 支架;再狭窄;西罗莫司
基金项目(Foundation):
作者(Author): 李忠红,衣为民,彭长农,龙娟,王丽丽
参考文献(References):
- 1MehranR,DangasG,AbizaidAS,etal.Angiographicpatternsofin stentrestenosis:classificationandimplicationsforlong termoutcome.Circulation,1999,100:18721878.
- 2El OmarMM,DangasG,IakovouI,etal.Updateonin stent restenosis.CurrInterventCardiolRep,2001,3:296305.
- 3WardehAJ,KnookAH,KayIP,etal.Clinicalandangiographical follow upafterimplantationofa612microradioactivestentinpatients withcoronaryarterydisease.EurHeartJ,2001,22:669675.
- 4CostaMA,SabatM,vanderGiessenWJ,etal.Latecoronary occlusionafterintracoronarybrachytherapy.Circulation,1999,100:789792.
- 5GalloR,PadureanA,ChesebroJH,etal.Inhibitionofintimal thickeningafterballoonangioplastyinporcinecoronaryarteriesby rapamycin.Circulation,1998,99:21642170.
- 6StevenO,AndrewR.Thedevelopmentofrapamycinanditsapplication tostentrestenosis.Circulation,2001,104:852855.
- 7DegertekinM,RegarE,SmitsPC,etal.Sirolimus elutingstentfor treatmentofin stentrestenosis:thefirstEuropeanclinicalexperience.EurHeartJ,2002,23(Suppl):265.