急性心肌梗死直接经皮冠状动脉介入治疗时间的临床研究Significance of symptom-to-ballon time on patients with ST elevation acute myocardial infarction treated with primary PCI
陈玉国,徐峰,张运,李继福,李贵双,纪求尚,吕瑞娟,孙祎,李瑞建
摘要(Abstract)：
目的探讨缩短直接经皮冠状动脉介入治疗(PCI)开始时间对ST段抬高急性心肌梗死(STEMI)的临床价值。方法171例STEMI,根据发病到开始PCI时间分为3组:<3h(A组,43例),≥3h、<6h(B组,58例),≥6h、<12h(C组,70例)。其中18例应用远端保护装置。比较3组术后TIMI3级率、ST段无回落率、左心室射血分数和住院期间主要不良心脏事件发生率。结果A组术后TIMI3级率和左心室射血分数显著高于B组和C组,ST段无回落率和住院期间主要不良心脏事件发生率均显著低于B组和C组。B组和C组比较,各指标差异均无统计学意义。结论在STEMI直接PCI中,与3h后开始PCI比较,3h内PCI可显著提高TIMI3级率,改善心肌组织再灌注、心功能和近期预后;3h后介入治疗无明显的时间依赖性。
关键词(KeyWords)： 心肌梗死;血管成形术,经腔,经皮冠状动脉;支架
基金项目(Foundation):
作者(Author): 陈玉国,徐峰,张运,李继福,李贵双,纪求尚,吕瑞娟,孙祎,李瑞建
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