冠心病心力衰竭患者血运重建术后心脏性猝死的危险因素评估——CRISIS临床研究Evaluation of risk factors for sudden cardiac death after revascularization in patients with coronary heart disease and heart failure
彭丁,王韶屏,柳景华,白雪莲
摘要(Abstract):
目的探讨冠心病心力衰竭患者血运重建术后心脏性猝死(sudden cardiac death,SCD)的高危因素。方法回顾性分析首都医科大学附属北京安贞医院2005年1月至2014年12月1683例行血运重建术且术前30 d内左心室射血分数(LVEF)≤40%的冠心病心力衰竭患者,根据随访期间是否发生SCD分为SCD组(59例)和无SCD组(1624例),评估住院期间临床基线资料、超声心动图、血管病变及用药情况。结果本研究平均随访(1803±994)d。Cox回归分析发现,三尖瓣反流(HR 2.217,95%CI 1.285~3.827,P=0.004)、左主干+三支病变(HR 3.089,95%CI 1.310~7.283,P=0.010)、尿酸(HR 1.003,95%CI 1.001~1.005,P=0.006)为SCD的独立预测因素。结论尿酸、冠状动脉左主干+三支病变、三尖瓣反流是冠心病心力衰竭患者血运重建术后发生SCD的独立预测因素。
关键词(KeyWords): 心力衰竭;冠心病;血运重建;高危因素
基金项目(Foundation): 国家重点基础研究发展计划(2015CB554404)
作者(Author): 彭丁,王韶屏,柳景华,白雪莲
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