顾菲菲,吕树铮,陈韵岱,宋现涛,吴小凡,金泽宁,周玉杰,霍勇

• 1:煤炭总医院心脏中心
• 2:首都医科大学附属北京安贞医院心内科
• 3:中国人民解放军总医院心内科
• 4:北京大学第一医院心内科

摘要(Abstract)：

目的应用血管内超声技术探讨不稳定性心绞痛患者冠状动脉临界病变的形态学特征。方法入选98例不稳定性心绞痛(UA,56例)或稳定性心绞痛(SA,42例)患者,经冠状动脉造影检查证实至少一支冠状动脉主要分支存在>20%且<70%局限狭窄,对符合条件的冠状动脉进行血管内超声检查。结果在病变部位,斑块面积(7.85±2.83)mm2比(6.53±2.92)mm2、斑块负荷(60.92±11.04)%比(53.87±17.52)%、重构指数(0.93±0.16)比(0.86±0.10)及偏心指数(0.74±0.17)比(0.66±0.21),在UA组高于SA组。正性重构在UA组比SA组更多见(28.6%比9.5%),偏心斑块及软斑块发生率在UA组更高(89.3%比71.4%)和(3.9%比16.7%)。结论冠状动脉临界病变的斑块负荷和重构指数在UA患者高于SA患者,UA组具有更多正性重构的患者,提示斑块的形态学与临床心绞痛的状态密切相关。

关键词(KeyWords)： 超声检查,介入性;心绞痛;动脉粥样硬化

Abstract:

Keywords:

基金项目(Foundation): 北京市科委重大科技计划项目(D0906006040191)

作者(Author): 顾菲菲,吕树铮,陈韵岱,宋现涛,吴小凡,金泽宁,周玉杰,霍勇

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