白明,张福,李强,潘明,汪涛,药素毓,黄晏,张钲

• 1:兰州大学第一医院心内科
• 2:兰州大学第一临床医学院

摘要(Abstract)：

目的比较无聚合物紫杉醇支架(垠艺)与聚合物紫杉醇涂层支架(TAXUS)用于冠心病患者的安全性及有效性。方法回顾分析兰州大学第一医院心脏中心置入垠艺支架治疗的75例冠心病患者和置入TAXUS支架治疗的59例冠心病患者,对比分析两组患者术后1年内主要不良心脏事件(MACE,包括心源性死亡、再发心绞痛或非致死性心肌梗死、再次靶血管血运重建)发生率、支架内血栓事件的发生率。结果两组除高血压例数外,在基本临床情况(包括年龄、性别、糖尿病、高脂血症、急性心肌梗死、不稳定型心绞痛、急性冠状动脉综合征、稳定型心绞痛)、冠状动脉病变特征(分叉病变、开口病变、三支病变、慢性完全闭塞病变、小病变、长病变、B2+C型病变)及基本介入技术指标(靶血管狭窄程度、病变长度、平均支架管径、平均支架长度)等方面差异均无统计学意义(P均>0.05);两组手术操作成功率均为100%,术后随访1年,主要心脏不良事件发生率垠艺组为5.6%,TAXUS组为7.0%,两组比较差异无统计学意义(P>0.05);TAXUS组支架内血栓1例,而垠艺组术后无支架内血栓事件发生,但两组比较差异无统计学意义(P>0.05)。结论无聚合物紫杉醇支架(垠艺支架)治疗冠心病安全有效,与TAXUS支架相比无明显差异。

关键词(KeyWords)： 冠状动脉疾病;支架;血管成形术,经腔,经皮冠状动脉

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 白明,张福,李强,潘明,汪涛,药素毓,黄晏,张钲

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