赖浚兴,谭文锋,宋岸坚,张斌

• 1:江门市中心医院心内科

摘要(Abstract)：

目的探讨ADROIT指引导管在对冠状动脉分叉病变行经皮冠状动脉介入治疗(PCI中应用的临床效果。方法纳入2015年9月至2017年9月就诊于江门市中心医院心内科需行PCI的分叉病变患者共120例,按照简单随机数字表法分为试验组(ADROIT指引导管组)60例和对照组(普通指引导管组)60例,比较两组患者手术时间、X线曝光时间(简称"曝光时间")、对比剂用量、手术成功率以及术后6个月支架内再狭窄发生率等。结果试验组患者总手术时间少于对照组[(49.2±19.5)min比(63.4±21.5)min,P<0.001],而曝光时间(双支架)高于对照组[(37.0±11.6)min比(29.3±5.9)min,P=0.037],差异均有统计学意义。两组患者均未发生明显夹层,手术成功率及支架内再狭窄发生率比较,差异均无统计学意义(均P>0.05)。单支架技术JWT患者手术时间、曝光时间及对比剂用量比较,差异均无统计学意义(均P>0.05)。结论 ADROIT指引导管在冠状动脉分叉病变行PCI中较普通指引导管手术时间更少,术中并发症发生率及术后中期效果与普通指引导管差异不大,能完成大部分分叉病变的治疗,值得临床推广。

关键词(KeyWords)： 指引导管;分叉病变;经皮冠状动脉介入治疗

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 赖浚兴,谭文锋,宋岸坚,张斌

参考文献(References)：

• [1]Wang XB,Han YD,Cui NH,et al.Associations of lipid levels susceptibility loci with coronary artery disease in Chinese population.Lipids Health Dis,2015,14:80.
• [2]Smilowitz NR,Feit F.The history of primary angioplasty and stenting for acute myocardial infarction.Curr Cardiol Rep,2016,18(1):5.
• [3]Redfors B,Généreux P.Peecutaneous coronary intervention for bifurcation lesions.Interv Cardiol Clin,2016,5(2):153-175.
• [4]Lee JM,Koo BK,Kumsars I,et al.Coronary fractional fl ow reserve in bifurcation stenosis:what have we learned?EuroIntervention,2015,11(Suppl):V59-V63.
• [5]Hou L,Wei YD,Li WM,et al.Comparative study on transradial versus transfemoral approach for primary percutaneous coronary intervention in Chinese patients with acute myocardial infarction.Saudi Med J,2010,31(2):158-162.
• [6]中华医学会心血管病学分会介入心脏病学组,中华心血管病杂志编辑委员会.中国经皮冠状动脉介入治疗指南2012(简本).中华心血管病杂志,2012,40(4):271-277.
• [7]Chen SL,Xu B,Han YL,et al.Comparison of double kissing crush versus culotte stenting for unprotected distal left main bifurcation lesions.J Am Coll Cardiol,2013,61(14):1482-1488.
• [8]Aldrich RF,Brensike JF,Battaglini JW,et al.Coronary calcifications in the detection of coronary artery disease and comparison with electrocardiographic exercise testing.Results from the national heart,lung,and blood Institute's typeⅡcoronary intervention study.Circulation,1979,59(6):1113-1124.
• [9]Kiemeneij F,Laarman GJ,Odekerken D,et al.A randomized comparison of percutaneous transluminal coronary intervention by the radial,brachial and femoral approaches:the access study.J Am Coll Cardiol,1997,29(6):1269-1275.
• [10]全勇,张育民,李峰,等.左、右侧桡动脉途径冠状动脉介入治疗的效果比较.临床合理用药杂志,2017,10(5):6-7.