生物可吸收支架治疗支架内再狭窄的研究进展
蔡金赞,朱永翔,朱灏,张瑶俊
摘要(Abstract):
<正>经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后出现支架内再狭窄(in-stent restenosis,ISR)已成为冠心病介入领域的一个难题。ISR首选治疗方式主要为药物洗脱球囊(drug-eluting balloon,DCB)和新一代药物洗脱支架(drug-eluting stent,DES),但两者均存在着各自的局限,且再次发生ISR的风险仍会很高。生物可吸收支架(bioresorbable scaff old,BRS)作为冠状动脉介入治疗领域的第四次变革,或许能给ISR患者带来崭新的治疗策略。本文将主要介绍ISR病变的治疗现状、BRS在ISR病变中的应用探索、腔内影像学技术指导BRS治疗ISR病变及未来展望。
关键词(KeyWords): 生物可吸收支架;支架内再狭窄;经皮冠状动脉介入治疗
基金项目(Foundation): 南京市科技计划项目(201503024);; 南京市医学科技发展资金资助项目(YKK15100);; 江苏省青年医学人才(QNRC2016065);; 江苏省六大人才高峰项目(WSN-219)
作者(Author): 蔡金赞,朱永翔,朱灏,张瑶俊
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