对比剂诱导急性肾损伤精细化预防策略的研究进展
陈汉川,何浩铭,何晨,严晗,王孙蓥,陈希男,朱鹏立,郭延松,林开阳
摘要(Abstract):
<正>对比剂诱导急性肾损伤(contrast-induced acute kidney injury,CI-AKI)也称为对比剂肾病(contrast-induced nephropathy,CIN),是对比剂使用后常见的并发症。随着放射学和心脏病学的发展,越来越多的患者接受CT检查和经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)。由于对比剂的使用越来越普遍,伴随而来的是CI-AKI这一严重并发症的增加。CI-AKI的发生会延长患者住院时间,增加医疗费用,增加透析、死亡等风险,严重影响患者健康,加重社会经济负担。然而,目前临床上针对CI-AKI尚缺乏有效的治疗手段,预防显得尤为重要。目前公认的有效预防CI-AKI的策略主要是充分水化和减少对比剂用量,然而其在
关键词(KeyWords): 对比剂诱导急性肾损伤;预防;水化;经皮冠状动脉介入治疗;介入放射学
基金项目(Foundation): 福建省自然科学基金项目(2017J01171);; 福建医科大学启航基金项目(2016QH113);; 福建省卫生计生面向农村和城市社区推广适宜技术项目(2017010)
作者(Author): 陈汉川,何浩铭,何晨,严晗,王孙蓥,陈希男,朱鹏立,郭延松,林开阳
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